| # | Children | Name | Born | Died | Father | Mother |
|---|
| 1 | | | b. 1785 | d. 18 Apr 1811 | Rev. Joseph Willis, Sr. (half Cherokee Indian) | Rachel Bradford (or Brasford) |
| 2 | Yes | | b. 1792 | | Rev. Joseph Willis, Sr. (half Cherokee Indian) | Rachel Bradford (or Brasford) |
| 3 | | | b. Abt 1787 | d. Yes, date unknown | Rev. Joseph Willis, Sr. (half Cherokee Indian) | Rachel Bradford (or Brasford) |
| 4 | | | b. 1794 | d. Yes, date unknown | Rev. Joseph Willis, Sr. (half Cherokee Indian) | Rachel Bradford (or Brasford) |
| 5 | | | b. 1796 | d. Yes, date unknown | Rev. Joseph Willis, Sr. (half Cherokee Indian) | Mrs. Sarah (..) Willis, (Irish woman) |
| 6 | | | b. 1798 | d. Yes, date unknown | Rev. Joseph Willis, Sr. (half Cherokee Indian) | Mrs. Sarah (..) Willis, (Irish woman) |
| 7 | Yes | | b. 6 Jan 1804 | d. Yes, date unknown | Rev. Joseph Willis, Sr. (half Cherokee Indian) | Sarah Johnson (?), (free colored) |
| 8 | Yes | | b. Abt 1812 | d. 1862 | Rev. Joseph Willis, Sr. (half Cherokee Indian) | Sarah Johnson (?), (free colored) |
| 9 | | | b. 1814 | d. Yes, date unknown | Rev. Joseph Willis, Sr. (half Cherokee Indian) | Sarah Johnson (?), (free colored) |
| 10 | | | b. Between 1809 and 1825 | d. Yes, date unknown | Rev. Joseph Willis, Sr. (half Cherokee Indian) | Sarah Johnson (?), (free colored) |
| 11 | | | b. 9 Apr 1825 | d. Yes, date unknown | Rev. Joseph Willis, Sr. (half Cherokee Indian) | Sarah Johnson (?), (free colored) |
| 12 | | | b. 1837 | d. Yes, date unknown | Rev. Joseph Willis, Sr. (half Cherokee Indian) | Elvy Sweat, (dau of who?) |
| 13 | | | b. 1 May 1837 | d. 9 Sep 1937 | Rev. Joseph Willis, Sr. (half Cherokee Indian) | Elvy Sweat, (dau of who?) |
| 14 | | | b. 1841 | d. Yes, date unknown | Rev. Joseph Willis, Sr. (half Cherokee Indian) | Elvy Sweat, (dau of who?) |
| 15 | | | b. 1845 | d. Yes, date unknown | Rev. Joseph Willis, Sr. (half Cherokee Indian) | Elvy Sweat, (dau of who?) |
| 16 | | | b. 1847 | d. Yes, date unknown | Rev. Joseph Willis, Sr. (half Cherokee Indian) | Elvy Sweat, (dau of who?) |
| 17 | | | b. 1848 | d. Yes, date unknown | Rev. Joseph Willis, Sr. (half Cherokee Indian) | Elvy Sweat, (dau of who?) |
Abt 1758 - 1854 (~ 96 years)