| # | Children | Name | Born | Died | Father | Mother |
| 1 | | | b. 3 Jul 1714 | d. 30 Nov 1734 | George Boone, IV | Deborah Howell |
| 2 | Yes | | b. 21 Apr 1716 | d. Aft 1739 | George Boone, IV | Deborah Howell |
| 3 | Yes | | b. 1 Oct 1718 | d. 8 Jul 1746 | George Boone, IV | Deborah Howell |
| 4 | | | b. Feb 1720 | d. Aft 1740 | George Boone, IV | Deborah Howell |
| 5 | Yes | | b. 29 Jan 1722 | d. Aft 1762 | George Boone, IV | Deborah Howell |
| 6 | | | b. 29 Nov 1724 | d. Abt 1770 | George Boone, IV | Deborah Howell |
| 7 | Yes | | b. 17 Mar 1727 | d. 1814 | George Boone, IV | Deborah Howell |
| 8 | | | b. 6 Sep 1729 | d. Aft 1730 | George Boone, IV | Deborah Howell |
| 9 | | | b. 20 Oct 1732 | d. Aft 1733 | George Boone, IV | Deborah Howell |
| 10 | Yes | | b. 2 Jun 1735 | d. 1823 | George Boone, IV | Deborah Howell |