| # | Children | Name | Born | Died | Father | Mother |
|---|
| 1 | | | b. 1836 | d. Aft 1850 | William Isaac Yoakum | Rachel Sisk, (full blood Cherokee) |
| 2 | | | b. 1838 | d. 1905 | William Isaac Yoakum | Rachel Sisk, (full blood Cherokee) |
| 3 | | | b. 1840 | d. Aft 1850 | William Isaac Yoakum | Rachel Sisk, (full blood Cherokee) |
| 4 | | | b. 1841 | d. Aft 1850 | William Isaac Yoakum | Rachel Sisk, (full blood Cherokee) |
| 5 | | | b. 20 May 1844 | d. 26 Feb 1925 | William Isaac Yoakum | Rachel Sisk, (full blood Cherokee) |
| 6 | Yes | | b. 26 Jul 1847 | d. 26 Jun 1902 | William Isaac Yoakum | Rachel Sisk, (full blood Cherokee) |
| 7 | | | b. 1847 | d. Aft 1850 | William Isaac Yoakum | Rachel Sisk, (full blood Cherokee) |
| 8 | | | b. 1849 | d. Aft 1850 | William Isaac Yoakum | Rachel Sisk, (full blood Cherokee) |
| 9 | | | b. 1854 | d. Aft 1870 | William Isaac Yoakum | Rachel Sisk, (full blood Cherokee) |
| 10 | | | b. 8 May 1854 | d. 8 Dec 1931 | William Isaac Yoakum | Rachel Sisk, (full blood Cherokee) |
| 11 | | | b. 1859 | d. Aft 1880 | William Isaac Yoakum | Rachel Sisk, (full blood Cherokee) |
1820 - 1905 (~ 84 years)