| # | Children | Name | Born | Died | Father | Mother |
|---|
| 1 | | | b. Between 18 Jul and 20 Oct 1834 | d. 18 Jul 1868 | Daniel John Keithley, Jr. | Elizabeth Hostetter |
| 2 | Yes | | b. 1835 | d. 1860 | Daniel John Keithley, Jr. | Elizabeth Hostetter |
| 3 | | | b. 1837 | d. Aft 1850 | Daniel John Keithley, Jr. | Elizabeth Hostetter |
| 4 | | | b. 8 Dec 1838 | d. 27 Jan 1899 | Daniel John Keithley, Jr. | Elizabeth Hostetter |
| 5 | | | b. Aug 1840 | d. 1 Jul 1913 | Daniel John Keithley, Jr. | Elizabeth Hostetter |
| 6 | | | b. 1843 | d. Aft 1860 | Daniel John Keithley, Jr. | Elizabeth Hostetter |
| 7 | | | b. 1844 | d. Aft 1850 | Daniel John Keithley, Jr. | Elizabeth Hostetter |
| 8 | | | b. 22 Feb 1845 | d. 1 Dec 1912 | Daniel John Keithley, Jr. | Elizabeth Hostetter |
| 9 | Yes | | b. 1847 | d. Aft 1870 | Daniel John Keithley, Jr. | Elizabeth Hostetter |
| 10 | | | b. 12 Feb 1849 | d. 25 Nov 1906 | Daniel John Keithley, Jr. | Elizabeth Hostetter |
| 11 | | | b. 1850 | d. Aft 1860 | Daniel John Keithley, Jr. | Elizabeth Hostetter |
| 12 | Yes | | b. 7 Feb 1854 | d. 20 Jul 1910 | Daniel John Keithley, Jr. | Rebecca H. Gose, (2nd wife) |
| 13 | | | b. 20 Mar 1856 | d. 13 Apr 1923 | Daniel John Keithley, Jr. | Rebecca H. Gose, (2nd wife) |
| 14 | | | b. 1858 | d. Aft 1870 | Daniel John Keithley, Jr. | Rebecca H. Gose, (2nd wife) |
| 15 | | | b. 1860 | d. Aft 1870 | Daniel John Keithley, Jr. | Rebecca H. Gose, (2nd wife) |
| 16 | | | b. 1862 | d. Aft 1870 | Daniel John Keithley, Jr. | Rebecca H. Gose, (2nd wife) |
| 17 | Yes | | b. Between 1861 and 1866 | d. Aft 1880 | Daniel John Keithley, Jr. | Rebecca H. Gose, (2nd wife) |
| 18 | | | b. 12 May 1868 | d. 7 Mar 1932 | Daniel John Keithley, Jr. | Rebecca H. Gose, (2nd wife) |
| 19 | Yes | | b. 24 Jan 1872 | d. 19 Mar 1943 | Daniel John Keithley, Jr. | Rebecca H. Gose, (2nd wife) |
1809 - 1883 (73 years)